According to Microsoft, the Xbox 360 has sold over 10 million units in the US - making it the first current-generation console to break that mark.
World-wide, the console has sold more than 19 million units and has attracted more than 12 million Xbox Live members.
"This year will be the largest in the history of the video gameindustry, with Xbox 360 leading the charge in the US and abroad," said Don Mattrick, senior VP of the Interactive Entertainment Business in the Entertainment and Devices Division at Microsoft.
"History has shown us that the first company to reach 10 million in console sales wins the generation battle. We are uniquely positioned to set a new benchmark for the industry."
Microsoft said that Xbox Live global membership - which has doubled in a year's time - was fueled by the recent launch of Grand Theft Auto IV.
The company also claims that the Xbox 360 has the industry's highest software attach rate - more than any other console this generation - and is home to more than 16 titles that have sold through one million units or more.