Kuju has rebranded its Sheffield studio as Chemistry.
The team will focus on development using Epic's Unreal Engine 3, on titles such as the forthcoming To End All Wars for publisher Ghostlight.
"We've decided to specialise in Unreal Engine as it's clearly an awesome next-gen toolset that frees our staff to focus on bringing their creative talents to bear without worrying about low-level nuts and bolts," said Simeon Pashley, studio head.
"It's also perfect for our future plans as at allows us to look forward without worrying about technology stability," he added.
The studio has recently completed a move into larger offices and intends to expand beyond its current 30 staff.
"Chemistry impressed us earlier this year with a very interesting UE3-based prototype and we're equally impressed with their business strategy as well," commented Mark Rein, vice president of Epic Games.
"By specialising in Unreal Engine 3 they're going to get continuously more proficient at using it and develop increasingly polished games over time. We know this strategy very well because it is exactly what we're planning."
The Sheffield rebranding follows Kuju's Brighton studio renaming itself Zoe Mode in March.