Activision's multiformat movie tie-in Spider-Man 3 is at the top of the All Formats charts for the fourth consecutive week.
Disney Interactive's Pirates of the Caribbean: At World's End enters the charts at number two this week, with Nintendo's Mario Strikers Charged Football debuting at number three.
EA's Xbox 360 and PC strategy title Command & Conquer 3: Tiberium Wars is at number four, with Konami's Pro Evolution Soccer 6 at number five.
Nintendo holds the sixth and seventh positions in the chart with Wii play and Dr Kawashima's Brain Training, respectively.
Tiger Woods PGA Tour 07 is at number eight this week, with another EA Sports title, FIFA 07 at number nine, and 505 Games' Cooking Mama at number ten.
Elsewhere in the charts, Eidos' DS title Pony Friends enters the top 40 at number 18 on its second week of release, while a renewed supply of Activision's Guitar Hero II has seen the title re-enter at number 24.
The only other new entry in the charts is Konami's Metal Gear Solid Portable Ops, at number 30.