Sony and Polyphony's Gran Turismo 5 has shipped 5.5 million units worldwide since launch, according to the format holder.
The entire Gran Turismo series has now passed 60 million unit sales since it was first launched in 1997.
The game was the eighth most-popular game in the US during November, behind EA's Need for Speed: Hot Pursuit.
The latest version of the game had suffered long delays, with Polyphony Digital boss Kazunori Yamauchi insistent that the game was perfect on release.
"Satisfying the loyal Gran Turismo followers is at the heart of all of our efforts, which is why it was such a difficult decision to delay the release of the game, and one which we did not take lightly," he said in November.
"I can only apologise to everyone for making you wait so long, and I hope that when you try out the wealth of driving experiences available in Gran Turismo 5, you will not be disappointed."